Clinical judgment for AI health advice

HUMAINE Health brings clinician expertise into the evaluation of AI health advice.

We combine realistic test conversations, blinded clinical review, and pressure testing to examine potentially harmful advice and the automated judgments used to detect it.

Health questions start in everyday life

People ask AI about symptoms, medication, food, and exercise. An ordinary conversation can contain details that change the clinical risk.

HUMAINE is Prolific’s research program exploring how people experience AI through conversations with anonymous models. HUMAINE Health builds test scenarios from the health questions people ask.

The test users are simulated; the model replies are real. This lets clinicians examine those replies without sharing participants’ private conversations.

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Why health advice needs clinical judgment

A preferred response can still contain harmful advice

In HUMAINE’s pilot comparisons, people chose replies with a classifier-flagged clinical problem about as often as unflagged replies. An answer can sound helpful while missing a risk.

Preference and clinical safety need separate assessments. We examine what people choose alongside how clinicians judge test responses, keeping the different tasks and samples explicit.

An automated judgment needs a clinical check

Given the same conversations and questionnaire, AI judges reached different conclusions. Similar overall error rates didn't necessarily mean agreement on individual cases.

Our method compares automated assessments with a clinician panel, examining where judgments align and differ, so an AI score isn't treated as a safety verdict on its own.

Put clinical expertise at the center

Build relevant scenarios
Turn the kinds of questions people ask into scripted everyday tests and conversations that challenge a model under pressure.
Bring clinicians into the review
Ask practising clinicians to assess model replies, including whether the response recognizes risk and gives appropriate advice.
Check automated evaluation
Give AI judges the clinical questionnaire and compare their assessments with those of the clinician panel.

Clinical expertise connects the details

In a simulated test, a person asks whether a thorn injury can wait until Saturday. They mention a retained thorn, methotrexate, vaccination history, and no redness or swelling.

The clinician’s task is to assess those details together: what did the response recognize, what did it overlook, and was the advice about seeking care appropriate?

This is the judgment the method is designed to capture. A fluent, reassuring response isn't enough to establish clinical safety.

Follow the advice beyond the first response

A model may recognise a risk at first, then change its advice when a user insists. Pressure tests use simulated users who push back across several turns.

Clinicians review the conversation to assess how the model responds as pressure and context develop. The question is whether appropriate advice holds up through the exchange.

These tests probe how failures can happen. They don't estimate how often those failures occur in everyday use.

A method designed for careful comparison

Verified clinical expertise
The research uses registered clinicians whose credentials are verified by Prolific, bringing professional judgment to the evaluation.
Blinded model assessment
Clinicians review replies without knowing which model produced them, keeping the assessment focused on the advice.
Shared questions, multiple reviewers
A common questionnaire makes judgments comparable. A panel makes disagreement visible instead of treating one reviewer as definitive.
FAQs

About the methodology

Discuss your healthcare AI evaluation

Talk to our team about the models, use cases, and clinical judgments you need to evaluate.